Research
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Research at Pars Medicine
Advancing medical knowledge through innovative research that transforms patient care. Our comprehensive research enterprise spans discovery science, clinical investigation, translational medicine, and population health studies.
Clinical Trials
Explore our active clinical trials and learn how to participate in groundbreaking research studies that advance medical treatments.
View Active TrialsResearch Programs
Discover our diverse research programs spanning basic science, translational research, and clinical investigation.
Explore ProgramsPrincipal Investigators
Meet our distinguished faculty researchers leading innovative studies across medical disciplines.
Meet Our ResearchersPublications
Access our peer-reviewed publications, research papers, and scholarly contributions to medical literature.
Browse PublicationsResearch Facilities
Tour our state-of-the-art research facilities, core laboratories, and specialized research centers.
View FacilitiesIRB & Research Ethics
Learn about our Institutional Review Board, ethical guidelines, and research compliance protocols.
Ethics InformationGrants & Funding
Explore funding opportunities, grant resources, and support services for researchers.
Funding ResourcesInnovation Lab
Discover our innovation initiatives, technology transfer, and entrepreneurship programs.
Explore InnovationResearch Focus Areas
Our investigators lead cutting-edge research programs addressing the most pressing health challenges of our time.
Cancer Biology & Therapeutics
Investigating molecular drivers of cancer, developing novel targeted therapies, immunotherapies, and precision oncology approaches across multiple tumor types.
Cardiovascular Research
Advancing understanding of heart disease mechanisms, developing innovative interventions for heart failure, arrhythmias, and vascular diseases.
Neuroscience & Brain Health
Exploring neural mechanisms, neurodegeneration, stroke recovery, and mental health disorders through integrated basic and clinical research.
Infectious Disease & Immunology
Combating emerging infections, antimicrobial resistance, and developing novel vaccines and immunotherapies.
AI & Digital Health
Leveraging artificial intelligence, machine learning, and digital technologies to transform diagnostics, treatment, and healthcare delivery.
Population Health & Equity
Addressing health disparities, studying social determinants of health, and developing community-based interventions for improved outcomes.
Quick Links
Connect with Our Research Team
Whether you are interested in participating in a clinical trial, exploring collaboration opportunities, or joining our research community, we are here to help.
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Our Research Programs
Pars Medicine is committed to advancing medical knowledge through innovative research programs that span multiple disciplines.
Clinical Research Programs
- Cardiovascular Research - Investigating novel treatments for heart disease and stroke prevention
- Oncology Research - Developing targeted therapies and immunotherapy approaches
- Neuroscience Research - Exploring treatments for neurological disorders
- Infectious Disease Research - Advancing vaccines and antimicrobial treatments
Basic Science Programs
- Genomics & Precision Medicine - Leveraging genetic insights for personalized treatment
- Immunology - Understanding immune system function and dysfunction
- Cell Biology - Investigating cellular mechanisms of disease
- Pharmacology - Developing and testing new therapeutic agents
Research Training
We offer comprehensive training programs for medical students, residents, fellows, and post-doctoral researchers pursuing research careers.
Get Involved
Contact our Research Office at
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Research Publications
Pars Medicine is committed to advancing medical knowledge through scholarly research. As our institution grows, our faculty and researchers will contribute to peer-reviewed publications in leading scientific journals.
Research Focus Areas
- Clinical Outcomes Research - Measuring treatment effectiveness and patient outcomes
- Healthcare Innovation - Technology-enabled care delivery models
- Population Health - Community-based health interventions
- Medical Education - Teaching methodologies and curriculum development
Publication Support
Faculty members seeking publication support can contact our Academic Affairs office for assistance with manuscript preparation and submission.
Note: Publication listings will be updated as our research programs develop. Check back for updates on faculty research and publications.
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Pars Medicine Innovation Lab
The Innovation Lab is our hub for developing cutting-edge healthcare technologies and solutions that improve patient outcomes and transform care delivery.
Our Focus Areas
AI & Machine Learning
- Clinical decision support systems
- Predictive analytics for patient outcomes
- Natural language processing for medical records
- Computer vision for diagnostic imaging
Digital Health
- Remote patient monitoring platforms
- Mobile health applications
- Wearable device integration
- Telehealth infrastructure
Medical Devices
- Point-of-care diagnostic tools
- Smart medical devices
- Sensor technologies
- Biomedical engineering solutions
Innovation Process
- Ideation - Identify clinical needs and opportunities
- Prototyping - Rapid development and testing
- Validation - Clinical trials and user testing
- Implementation - Deployment and scaling
Partner With Us
We collaborate with startups, industry partners, and academic institutions. Contact
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Research Opportunities
Advancing knowledge through discovery and innovation
At Pars University, research is central to our mission. Students at all levels have opportunities to engage in meaningful research that advances healthcare knowledge and improves patient outcomes.
Student Research Programs
Summer Research Fellowship
10-week intensive research experience with faculty mentors. Stipend provided.
For: MD, PhD, and graduate students
Apply: February 1 deadline
Research Scholars Program
Year-long program integrating research into curriculum with dedicated mentorship.
For: Medical students (MS1-MS4)
Benefits: Research credits, conference funding
Graduate Research Assistantships
Work with faculty on funded research projects. Tuition waiver and stipend.
For: MPH, MSN, PhD students
Hours: 10-20 hours/week
Research Focus Areas
- Cancer Biology and Therapeutics
- Cardiovascular Disease
- Infectious Diseases
- Neuroscience and Neurodegeneration
- Healthcare Disparities
- Implementation Science
- Digital Health and AI
- Global Health
- Clinical Trials
- Health Policy Research
Research Resources
- Core Facilities: Flow cytometry, genomics, imaging, biostatistics
- Grant Support: Office of Sponsored Programs assists with applications
- IRB Services: Streamlined human subjects research approval
- Biobank: Access to de-identified specimens for approved research
Get Involved in Research
Contact the Office of Research to learn about current opportunities.
Email:
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Clinical Research at Pars Medicine
Advancing medical care through rigorous, ethical research. Explore our 200+ active clinical trials and discover how you can contribute to breakthrough treatments that benefit patients worldwide.
Active Clinical Trials
We conduct over 200 active clinical trials spanning all phases (Phase I-IV) across multiple therapeutic areas. Here are some of our featured studies:
Advanced Breast Cancer Immunotherapy
Evaluating a novel combination of checkpoint inhibitors with targeted therapy for HER2-positive metastatic breast cancer.
Eligibility: Adults 18+ with confirmed HER2+ breast cancer
Heart Failure Gene Therapy
Testing an innovative gene therapy approach to restore cardiac function in patients with chronic heart failure.
Eligibility: Adults 40-75 with NYHA Class II-III heart failure
Early Alzheimer's Disease Treatment
Investigating a disease-modifying antibody therapy targeting amyloid plaques in early-stage Alzheimer's disease.
Eligibility: Adults 55-85 with mild cognitive impairment
Type 2 Diabetes Novel Therapy
Studying a new dual-action medication that improves both insulin sensitivity and beta cell function.
Eligibility: Adults 18+ with Type 2 diabetes, A1C 7.5-10%
Rheumatoid Arthritis Biologic
Evaluating a next-generation JAK inhibitor for patients with moderate-to-severe RA who have not responded to standard biologics.
Eligibility: Adults 18+ with active RA despite prior treatment
Severe Asthma Biologic Therapy
Testing a new biologic targeting multiple inflammatory pathways in patients with uncontrolled severe asthma.
Eligibility: Adults 18-65 with severe eosinophilic asthma
How to Participate
Participating in a clinical trial may provide access to promising new treatments while contributing to medical research. Follow these steps to get started:
Search for Trials
Use our Clinical Trials Search Tool or browse ClinicalTrials.gov for studies matching your condition.
Contact Research Team
Each trial listing includes contact information. Reach out to learn more about the study and express your interest.
Screening & Eligibility
Our team reviews your medical history to determine if you meet the specific inclusion criteria for the trial.
Informed Consent
Review detailed study information including purpose, procedures, risks, and benefits. Take time to ask questions.
Enrollment
If you choose to enroll, you'll undergo baseline evaluations and begin the study with regular monitoring visits.
Patient Safety & Protections
Your safety and wellbeing are our highest priorities. All clinical trials include comprehensive safeguards:
IRB Oversight
Every trial is reviewed and approved by our independent Institutional Review Board, including physicians, scientists, ethicists, and community members who ensure studies are ethical and scientifically sound.
Informed Consent
You'll receive detailed information about the study and provide voluntary written consent. Consent is ongoing - ask questions or withdraw at any time.
Safety Monitoring
Research teams closely monitor for adverse events. Independent Data Safety Monitoring Boards review safety data with authority to modify or stop studies if needed.
Your Rights
Understand all procedures, ask questions anytime, decline without affecting care, withdraw at any time, and have your information kept confidential.
Potential Benefits
- Access to new treatments not yet widely available
- Close monitoring by expert research teams
- Contribute to medical knowledge for future patients
- No cost for study-related care and treatments
- Possible compensation for time and travel
Potential Risks
- Unknown side effects from investigational treatments
- New treatment may not be effective
- Additional time commitment for study visits
- May require extra tests or procedures
- Possible randomization to standard treatment
Contact Our Research Team
Ready to learn more? Our clinical trials team is here to help you find the right study and answer your questions.
Patient Inquiries
Call: 1-833-PARS-MED ext. 225
Physician Referrals
Call: 1-833-PARS-MED ext. 250
We are committed to diversity, equity, and inclusion in clinical research. We actively recruit participants from diverse backgrounds and provide language assistance, transportation support, and flexible scheduling to reduce barriers to participation.
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Basic Research Programs
Basic research at Pars Medicine explores fundamental mechanisms of biology, disease, and health to generate new knowledge that forms the foundation for future medical breakthroughs. Our basic scientists investigate questions at the molecular, cellular, and systems levels, using cutting-edge technologies to understand how biological processes work in health and go awry in disease.
Mission and Approach
Our basic research mission is to uncover fundamental biological principles that will ultimately transform medical care. We pursue curiosity-driven research asking: How do cells communicate? What makes cancer cells grow uncontrollably? How does the brain process information? What determines the balance between health and disease? These fundamental questions generate insights that lead to new diagnostics, therapeutics, and preventive strategies.
We embrace an interdisciplinary approach, bringing together expertise from molecular biology, biochemistry, genetics, immunology, neuroscience, pharmacology, and computational biology. Our researchers collaborate across traditional disciplinary boundaries, applying diverse methodologies to complex biological questions.
Research Focus Areas
Cancer Biology
Understanding the molecular and cellular mechanisms driving cancer initiation, progression, metastasis, and therapeutic resistance. Research areas include:
- Oncogenic signaling pathways and tumor suppressor mechanisms
- Cancer stem cells and tumor heterogeneity
- Tumor microenvironment and cancer-immune system interactions
- DNA damage response and genomic instability
- Epigenetic alterations in cancer
- Metabolism in cancer cells
- Mechanisms of metastasis and cancer dormancy
Immunology and Host Defense
Investigating how the immune system protects against infection and cancer while maintaining tolerance to self. Key research areas include:
- Innate and adaptive immune responses
- T cell and B cell biology
- Immune tolerance and autoimmunity
- Immunometabolism and immune cell function
- Mucosal immunity and microbiome interactions
- Vaccine development and immune memory
- Inflammatory pathways and resolution of inflammation
Neuroscience
Exploring brain structure, function, development, and disease at multiple scales from molecules to neural circuits. Research encompasses:
- Neural development and brain plasticity
- Synaptic transmission and neural circuits
- Neurodegeneration and protein aggregation
- Neuroinflammation and neuroimmunology
- Neurotransmitter systems and signaling
- Learning, memory, and cognitive function
- Neural stem cells and regeneration
Cardiovascular Biology
Understanding heart and blood vessel function in health and disease. Areas of investigation include:
- Cardiac development and congenital heart defects
- Cardiac electrophysiology and arrhythmia mechanisms
- Heart failure and cardiac remodeling
- Atherosclerosis and vascular biology
- Angiogenesis and vascular development
- Cardiac metabolism and energetics
- Cardiomyocyte biology and regeneration
Metabolic and Endocrine Disorders
Studying metabolic regulation and endocrine function. Research focuses on:
- Insulin signaling and glucose metabolism
- Adipocyte biology and obesity
- Mitochondrial function and metabolic disease
- Lipid metabolism and dyslipidemia
- Hormonal regulation of metabolism
- Energy balance and appetite control
- Metabolic liver disease
Genetics and Genomics
Leveraging genomic technologies to understand genetic contributions to health and disease:
- Gene regulation and transcriptional control
- Chromatin structure and epigenetic modifications
- Non-coding RNA function
- Genetic variation and disease susceptibility
- Genome editing and CRISPR technologies
- Single-cell genomics and cellular heterogeneity
- Computational genomics and bioinformatics
Infectious Disease and Microbiology
Investigating host-pathogen interactions and microbial pathogenesis:
- Viral replication and immune evasion
- Bacterial pathogenesis and antimicrobial resistance
- Host innate immune responses to infection
- Microbiome composition and host-microbe interactions
- Emerging infectious diseases
- Fungal and parasitic infections
Stem Cell Biology and Regenerative Medicine
Exploring stem cell properties and regenerative potential:
- Embryonic and adult stem cell biology
- Induced pluripotent stem cells (iPSCs)
- Tissue regeneration and repair mechanisms
- Organoid development and disease modeling
- Stem cell differentiation and fate determination
- Tissue engineering approaches
Research Laboratories and Principal Investigators
Our basic research programs are led by over 80 principal investigators directing independent research laboratories. Each lab focuses on specific research questions while contributing to broader departmental and institutional research themes. Faculty investigators hold positions in departments including:
- Department of Biochemistry and Molecular Biology
- Department of Microbiology and Immunology
- Department of Neuroscience
- Department of Pharmacology
- Department of Physiology
- Department of Cell and Developmental Biology
- Department of Genetics and Genome Sciences
Core Facilities and Technologies
Basic researchers have access to state-of-the-art core facilities providing advanced technologies:
- Genomics Core - Next-generation sequencing, RNA-seq, ChIP-seq, ATAC-seq, single-cell sequencing
- Proteomics and Mass Spectrometry - Protein identification, post-translational modifications, metabolomics
- Flow Cytometry - Multi-parameter cell analysis and cell sorting
- Imaging Core - Confocal, two-photon, electron microscopy, live-cell imaging
- Bioinformatics - Computational analysis, data visualization, algorithm development
- Transgenic and Genome Editing - CRISPR/Cas9, mouse models, viral vectors
- Structural Biology - X-ray crystallography, cryo-EM, NMR spectroscopy
Publications and Impact
Basic research at Pars Medicine generates high-impact discoveries published in leading scientific journals including Nature, Science, Cell, and specialized journals across disciplines. Our faculty publish over 400 research articles annually, advancing knowledge across biomedical sciences.
Recent notable discoveries include:
- Identification of novel molecular pathways regulating cancer metastasis
- Development of new CRISPR-based gene editing tools
- Discovery of immune checkpoint molecules with therapeutic potential
- Elucidation of neural circuits underlying memory formation
- Characterization of metabolic pathways in cardiovascular disease
Training and Education
Basic research laboratories provide exceptional training environments for graduate students, postdoctoral fellows, and undergraduate researchers. Training programs include:
- PhD Programs - Biomedical Sciences graduate program with diverse specializations
- MD/PhD Program - Combined physician-scientist training
- Postdoctoral Fellowships - Advanced research training across disciplines
- Summer Research Programs - Undergraduate research experiences
- Research Rotations - Laboratory exposure for medical and graduate students
Funding Support
Basic research programs are supported by competitive funding from NIH, NSF, American Heart Association, American Cancer Society, private foundations, and institutional resources. Our Office of Research provides grant writing support, regulatory guidance, and research administration.
Collaboration and Resources
We foster collaborative research through:
- Departmental and interdisciplinary seminar series
- Research symposia and retreats
- Shared core facilities and equipment
- Pilot grant programs for collaborative projects
- Partnerships with other academic institutions and industry
For more information: Explore our Faculty Research Directory, contact the Office of Basic Research at
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Translational Research
Translational research is the vital bridge connecting laboratory discoveries to clinical practice and public health impact. At Pars Medicine, our translational research programs accelerate the journey from bench to bedside and back again, ensuring that scientific breakthroughs improve patient care and that clinical observations generate new research questions. We are committed to translating knowledge into action to benefit patients and communities.
The Translational Research Vision
Translational research encompasses the full spectrum from basic discovery through clinical implementation and population health impact. We conceptualize translation as a bidirectional, iterative process:
- T0 Research - Basic biomedical research generating foundational knowledge
- T1 Translation - Moving discoveries from laboratory to human clinical trials
- T2 Translation - Establishing efficacy and effectiveness of interventions in clinical practice
- T3 Translation - Implementing evidence-based interventions in communities and health systems
- T4 Translation - Evaluating population health impact and informing policy
This comprehensive approach ensures that discoveries reach patients efficiently while clinical insights inform future research.
Translational Research Programs
Drug Discovery and Development
Our drug development pipeline spans target identification through clinical trials:
- Target Discovery and Validation - Identifying disease-relevant molecular targets using genomics, proteomics, and functional studies
- Hit-to-Lead Optimization - Screening compound libraries, optimizing drug-like properties, and medicinal chemistry
- Preclinical Development - Testing pharmacokinetics, toxicology, efficacy in animal models, and formulation
- IND-Enabling Studies - GMP manufacturing, regulatory preparation, and Investigational New Drug applications
- Clinical Trials - Phase I-III trials evaluating safety, dosing, efficacy, and comparative effectiveness
Recent drug development successes include novel targeted therapies for cancer, cardiovascular disease treatments, and antimicrobial agents now in clinical trials.
Biomarker Discovery and Validation
Identifying and validating biomarkers for disease diagnosis, prognosis, treatment selection, and monitoring:
- Multi-omics approaches (genomics, proteomics, metabolomics) for biomarker discovery
- Development of diagnostic assays and companion diagnostics
- Clinical validation studies establishing biomarker utility
- Integration of biomarkers into clinical decision-making
- Liquid biopsy development for non-invasive disease monitoring
Medical Device and Technology Development
Translating engineering innovations into clinical applications:
- Diagnostic devices and point-of-care testing platforms
- Implantable devices (cardiac devices, neural implants, drug delivery systems)
- Wearable sensors and remote monitoring technologies
- Surgical instruments and minimally invasive technologies
- Digital health tools and mobile health applications
- Artificial intelligence and machine learning for clinical decision support
Cell and Gene Therapy
Developing advanced cellular and genetic therapies:
- CAR-T cell therapy for cancer and autoimmune diseases
- Gene therapy vectors and delivery systems
- Genome editing approaches (CRISPR/Cas9, base editing, prime editing)
- Stem cell therapies for regenerative medicine
- Manufacturing and quality control for cell-based therapies
- Clinical trials evaluating safety and efficacy
Precision Medicine and Pharmacogenomics
Personalizing treatment based on individual patient characteristics:
- Genomic profiling to guide cancer therapy selection
- Pharmacogenomic testing for drug dosing and selection
- Integration of multi-omic data for treatment decisions
- Clinical implementation of precision medicine approaches
- Health equity in precision medicine
Imaging and Diagnostic Technologies
Advancing diagnostic imaging capabilities:
- Novel imaging probes and contrast agents
- Advanced MRI, PET, and CT imaging techniques
- Molecular imaging for early disease detection
- Image-guided therapies and interventions
- Artificial intelligence for image analysis and interpretation
Infrastructure and Resources
Pars Medicine provides comprehensive infrastructure supporting translational research:
Translational Research Centers
- Center for Drug Discovery and Development - High-throughput screening, medicinal chemistry, pharmacology
- Institute for Precision Medicine - Genomic medicine, bioinformatics, precision diagnostics
- Cell and Gene Therapy Center - GMP manufacturing, vector production, clinical cell therapy
- Biomarker Development Laboratory - Biomarker discovery, assay development, clinical validation
- Medical Device Innovation Center - Prototyping, testing, regulatory support for device development
Core Facilities
- GMP manufacturing facility for investigational products
- Biorepository with clinical specimens linked to outcomes data
- Phase I Clinical Research Unit for early-stage trials
- Genomics and proteomics cores
- Preclinical imaging facility
- Bioinformatics and computational biology resources
Regulatory and Administrative Support
- Office of Regulatory Affairs providing FDA/IND support
- Clinical Trials Office for study design and implementation
- Technology Transfer Office for patents, licensing, and commercialization
- IRB and IACUC for ethical oversight
- Quality assurance and regulatory compliance support
Partnerships and Collaboration
Successful translation requires diverse partnerships:
Academic Collaborations
Multi-institutional collaborations leveraging complementary expertise, sharing resources, and conducting multi-center trials.
Industry Partnerships
Collaborations with pharmaceutical, biotechnology, and medical device companies for co-development, licensing, and clinical trials. Partnerships accelerate translation while supporting institutional research.
Clinical Practice Integration
Embedded translational research within clinical care settings, enabling rapid clinical testing and implementation while ensuring patient access to innovations.
Community Engagement
Partnership with patient advocacy groups, community organizations, and patients to ensure research addresses real-world needs and benefits diverse populations.
Recent Translational Achievements
- First-in-human trials of novel cancer immunotherapy developed in institutional laboratories
- FDA approval of diagnostic biomarker test for cardiovascular disease risk
- Implementation of pharmacogenomic testing into routine clinical care
- Development of wearable device for continuous glucose monitoring
- CAR-T cell therapy trials for refractory hematologic malignancies
- Gene therapy trials for inherited retinal diseases
- AI-based diagnostic tool for early detection of sepsis
Training and Education
We train the next generation of translational scientists through:
- Translational Science Training Programs - Interdisciplinary training in translational research methods
- KL2 Career Development Awards - Mentored career development for junior translational investigators
- Clinical Research Training - Programs for clinician-scientists conducting translational studies
- Regulatory Science Education - Training in FDA processes, GCP, and regulatory requirements
- Entrepreneurship Programs - Supporting commercialization and startup development
Funding and Support
Translational research programs are supported by:
- NIH Clinical and Translational Science Awards (CTSA)
- Disease-focused foundations and advocacy organizations
- Industry-sponsored research agreements
- Institutional pilot grants and gap funding
- Venture capital and angel investment for startups
Impact Metrics
Our translational research enterprise generates measurable impact:
- 15-20 IND applications filed annually
- 50+ active early-phase clinical trials
- 100+ patents issued over past five years
- 25+ technology licenses executed
- Multiple FDA-approved therapies originating from institutional research
- Startup companies launched based on discoveries
For more information: Contact the Office of Translational Research at